Endorphin refers to a neuropeptide produced by the pituitary gland having pain-suppressing activity.

Endorphin is a chemical that is naturally produced in the brain and that causes Analgesia. Endorphins, is likewise defined as category of chemicals the body produces that stimulate the same receptors as do Opiates; neurotransmitters which are concentrated in the pituitary gland and parts of the brain, that inhibit physical pain. Endorphins are most prominent neuropeptide with opioid properties and have received much scientific attention for their analgesic effects and their possible role in a pain-inhibiting neuronal system.

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