Astrocyte (astroglia) refers to the relatively large, star-shaped glia cell. Moreover, Astrocytes are non-neural, star-shaped glia cells that are highly branched and occupy much space between neurons in the gray matter. Their multiple functions include supporting neurons by interweaving among nerve fibers, contributing to the metabolism of synaptic transmitters, and regulating the balance of ions. Astrocytes join together to provide a barrier between parts of the central nervous system (CNS) and non-CNS tissue.