MAOIs (Monoamine oxidase inhibitors) refer to the group of antidepressant drugs that inhibit the enzyme monoamine oxidase (MAO) in the brain and raise the levels of certain neurotransmitters , such as norepinephrine , dopamine , and serotonin . MAOIs are potent anti-depressants thought to regulate chemicals in the central nervous system ; they should rarely be the first medication used because they may interact dangerously with many other medications, foods and beverages

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