Rett Syndrome refers to a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. The key features of this syndrome are: (1) loss of purposeful use of the hand which is replaced with stereotyped hand-wringing; (2) screaming fits and inconsolable crying; (3) loss of speech; (4) behavior like that of autism; (5) panic-like attacks; (6) grinding of teeth (bruxism); and (7) microcephaly, among others

Rett Syndrome is also called Rett's Disorder.

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