Rett Syndrome refers to a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females. The key features of this syndrome are:

(1) loss of purposeful use of the hand which is replaced with stereotyped hand-wringing;

(2) screaming fits and inconsolable crying;

(3) loss of speech;

(4) behavior like that of autism;

(5) panic-like attacks;

(6) grinding of teeth (bruxism); and

(7) microcephaly, among others

Rett Syndrome is also called Rett's Disorder.

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