Alpha 2-adrenergic agonist refers to a
drug that reduces the
activity of the
neurotransmitter norepinephrine by stimulating certain
receptors within the central
nervous system (central presynaptic alpha 2-adrenergic receptors). The release of norepinephrine
triggers action within the sympathetic nervous system. This part of the nervous
system regulates certain involuntary activities during
stress, such as increasing the heart rate, deepening breathing, and raising blood
pressure. Norepinephrine also plays a role in regulating
mood and
emotion.
The
administration of
Alpha 2-adrenergic agonists may result in a reduced heart rate and lowered
blood pressure and have depressive or
sedative effects.