Amyotrophic lateral sclerosis refers to the disease of the Motor System in which people experience a gradual to total loss of muscle Control and muscle function.

Moreover, Amyotrophic lateral sclerosis is a progressive neuromuscular disease that causes degeneration of the nerve cells that control the movement of voluntary muscles (the motor neurons). These cells extend from the brain to the spinal cord (the upper motor neuron) and from the spinal cord to the muscles throughout the body (the lower motor neurons). The disease causes the motor neurons to degenerate and eventually die. As they die, the corresponding muscles become paralysed.

Amyotrophic Lateral Sclerosis is also called ALS and is also known as Lou Gehrig's disease.

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