Fragile-X syndrome refers to a chromosomal abnormality in which one area on the X chromosome is pinched. Children with Fragile-X syndrome typically suffer from moderate mental retardation. Moreover, Fragile-X syndrome is defined as a pattern of abnormality caused by a defect in the X chromosome resulting in mental retardation, learning problems, and unusual physical characteristics. Fragile-X syndrome is also spelled Fragile X syndrome (see Fragile-X syndrome)
Other /More definition:
fragile-X syndrome refers to a chromosomal abnormality in which one area on the X chromosome is pinched. Children with fragile-X syndrome typically suffer from moderate mental retardation.

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