Osteogenesis Imperfecta or OI refers to a disease caused by an abnormality in the collagen protein that the body requires for bones as well as other structures, such as teeth, ligaments and skin. The condition often leads to an increased likelihood of fractures, as well as fragile teeth, lax joints, bruising and blue or grey sclera (whites of eyes). Some people with brittle bone diseases develop deafness and some have short stature. Osteogenesis Imperfecta (OI) is also known as Brittle bone disease

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Osteokinematic motion refers to motion of the bones relative to the three (3) cardinal planes, resulting from physiological movements.

Osteoporosis refers to a disease characterized by a reduction in bone density, brittleness of bones, and a loss of calcium from the bones.

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Ostomies refers to the operations to remove part of the small or large intestine or the bladder, resulting in the need to create an artificial opening in the body for the elimination of bodily wastes.

Ostracism means excluding a person or group of people from a group, often by ignoring, shunning, or explicitly banishing them. Ostracism, moreover, is being excluded, rejected, and ignored by others

- Oswald Külpe (1862 - 1915) : Oswald Külpe applied systematic, experimental introspection to the study of problem solving and found that some mental operations are imageless.

OT is the abbreviations of Occupational therapy which is designed to help patients improve their independence with activities of daily living through exercises, rehabilitation, and the use of assistive devices.

Otitis media refers to the infection of the middle ear. This is frequently associated with fluid buildup in the middle ear (Otitis media with effusion), which results in temporary hearing impairment. Otitis media, moreover, is a common bacterial infection of the middle ear that produces mild to moderate hearing loss.